The Portuguese full-back finishes paperwork for Wolves as an immediate swap for the withdrew Matt Doherty, who left the club for Spurs prior this late spring.
The club had just reinforced the situation with the marking of Ki-Jana Hoever from Liverpool - yet Semedo offers a more experienced alternative on the correct flank, having shown up for Barcelona.
Semedo has marked an arrangement that will keep him at Molineux until 2023, with an alternative to reach out until 2025 in the club's courtesy.
Wolves will pay an underlying £27.5m for the 26-year-old, in spite of the fact that additional items could see that ascent to £29m and conceivably significantly more should certain triggers be hit.
Jeff Shi hailed the marking, naming Semedo as an 'elite's securing for the club.
"'Reformist on a basic level' is one of our guiding principle at Wolves. For an individual from staff, for a player, for the entire club, we are largely putting forth incredible attempts to advance persistently.
"It is a rarity indeed that's we have the chance to sign a top notch player from an a-list club. Nelson's marking shows we will never quit advancing and we are as yet ravenous and humble in our heart."
Semedo could highlight in Wolves' next game, as they're because of movement to West Ham this end of the week.
The protector is eager to begin his Wolves profession and is confident the side can break into the main six during his time at Molineux.
"I picked Wolves since it's an excellent group that plays awesome football. A year ago they did an awesome season and it's a significant group in England, in likewise Europe. I trust this year we can do generally excellent things." he said.
"Mentor Nuno is a generally excellent mentor. He did generally excellent things here in Wolves, and in different groups as well. Without a doubt I will a great deal from him.
"The group did awesome things the most recent three years. I'm driven and I trust this year we can do awesome things, arrive at the main six and, if it's conceivable, accomplish something unique.
"I'm glad to be here. I'm eager to begin and thank you kindly for your help and we will it together.
"I can bring the group pace, speed. I like to go ahead and return. They can anticipate a great deal of work and a ton of desire.
"I'm eager to be here. It's an excellent group. To play in the Premier League is a fantasy from me as well. Thus, I'm eager to start, to meet my partners and begin preparing."